In women, every month, until after menopause an egg is released with help from the Luteining follicle hormone and this increases progesterone.  Sometimes, however, no egg is released and no progesterone is secreted rather estrogen production increases.  As a result of this imbalance the follicles mature into fluid-filled sacs or cysts that grow larger every month until progesterone is released.

Micro-needling is an innovation in aesthetic medicine for the treatment of wrinkles, acne scars, hypertrophic scars, melasma, periorbital melanosis (darkness around eyes), stretch mark, androgenetic alopecia, and enlarged pores. During this procedure, tiny disposable needles are used to create controlled micro-injuries. The micro-channeling causes the release of growth factors that promote scar-less healing. Normal woven collagen rather than scar collagen is deposited at the treated site. Collagen formation through normal wound healing process (inflammation, proliferation, remodeling) can be seen in 12 weeks. After micro-needling treatment, slight edema (swelling) which resolves in 24 hours and mild erythema (redness) lasting 2-4 days is expected. Usually the number of sessions and the interval between sessions are dependent on the skin condition.